A new dawn in modern perio-diagnostics: Saliva and gingival crevicular fluid

Gingival Crevicular Fluid Biomarkers

Material and Method: Thirty patients were allocated into 3 groups: 10 were treated with scaling and root planing (SRP) only; 10 were treated with SRP and received adjunctive local metronidazole; 10 were treated with SRP and received adjunctive systemic metronidazole. Periodontal clinical parameters including plaque index, sulcus bleeding index, probing depth and relative attachment level were r...

Hepatocyte Growth Factor Levels in the Saliva and Gingival Crevicular Fluid in Smokers with Periodontitis

Hepatocyte growth factor (HGF) production by oral fibroblasts is enhanced by various molecules that are induced during inflammatory conditions including periodontitis. HGF plays an important role in the progression of periodontitis, by stimulating intense growth of epithelial cells and preventing regeneration of connective tissue attachments. Smokers have a greater risk factor in the pathogenes...

Hydroxyproline titers in gingival crevicular fluid.

Proinflammatory Cytokines in the Saliva, Gingival Crevicular Fluid and Serum of Diabetic Patients with Periodontal Disease

Periodontal disease (PD) is a complication of diabetes mellitus (or diabetes). Various proinflammatory cytokines are expressed in the saliva, gingival crevicular fluid (GCF) and serum of diabetic patients with PD. The aim of this study was to review the proinflammatory cytokinees that are expressed in the saliva, GCF and serum of diabetic patients with PD. The addressed focused question was "Wh...

superoxide dismutase enzyme and thiol antioxidants in gingival crevicular fluid and saliva

background: the possibility of impaired antioxidant status and so increased oxidative damage in periodontal disease is being conjectured. the present randomized controlled study was carried out with the objective of analyzing the activity of superoxide dismutase enzyme and thiol antioxidants in gingival crevicular fluid (gcf) and saliva as indicators of response to periodontal therapy. material...